Can judge interrupt a game if a mandatory trigger miss in high opl?

Yes — a judge may pause a match to address a missed mandatory trigger at high OPL. Nothing in the Tournament Rules restricts judges to acting only when called: the Head Judge is explicitly responsible for ensuring rules are followed and violations are dealt with (TR 204.4.a–b), and judges may act on what they observe, including spectator alerts (TR 204.8.c).

Interrupting doesn't change the remedy, though. If the trigger was missed in the current turn, the next opponent in turn order decides whether it resolves immediately or is missed entirely (TR 702.2.f.2); if it was missed in a previous turn, play just continues (TR 702.2.f.1). A forgotten trigger never goes on the Chain (TR 506.4). In practice, judges at high OPL usually intervene proactively only for integrity concerns — suspected cheating, repeated errors, or pattern of missed advantageous mandatory triggers (TR 702.2.e, 704.8) — and leave routine missed triggers to be flagged by the players via a judge call (TR 412.1).